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Activity Number: 355 - Contributed Poster Presentations: Biopharmaceutical Section
Type: Contributed
Date/Time: Tuesday, July 30, 2019 : 10:30 AM to 12:20 PM
Sponsor: Biopharmaceutical Section
Abstract #304693
Title: Sample Size Calculation for the Andersen-Gill Model Comparing Rates of Recurrent Events
Author(s): Ronan Fitzpatrick* and Yongqiang Tang
Companies: Statsols and Tesaro
Keywords: Sample Size; Statistical Power; Recurrent Events; Andersen-Gill Model; Non-inferiority; Equivalence

Recurrent events arise frequently in biomedical research, where the subject may experience the same type of events more than once. The Andersen-Gill (AG) model has become increasingly popular in the analysis of recurrent events particularly when the event rate is not constant over time. We propose a procedure for calculating the power and sample size for the AG model in superiority, non-inferiority and equivalence clinical trials.

Authors who are presenting talks have a * after their name.

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