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Activity Number: 617 - Testing
Type: Contributed
Date/Time: Thursday, August 1, 2019 : 8:30 AM to 10:20 AM
Sponsor: Biometrics Section
Abstract #301799
Title: Correlation of Sequential Binomial Variables and Its Application to Multiple Testing
Author(s): Lin Fei* and Changchun Xie
Companies: Cincinnati Children's Hospital Medical Center and University of Cincinnati
Keywords: binomial variable; conditional testing; multiplicity adjustment

We study a sequential testing of conditional binomial probabilities to assess incremental rates of success of several interventions. This design is more efficient than parallel procedures. In order to make use of dependent relationship among test statistics, thus to control family-wise error rate, we obtained an recursive procedure to calculate correlations for the sequence of observed binomial random variates. They were derived through conditioning on the natural filtration associated to the test statistics.

Authors who are presenting talks have a * after their name.

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