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Activity Number: 156 - Statistical Interactions – Making an Impact in Health Science
Type: Topic Contributed
Date/Time: Monday, July 29, 2019 : 10:30 AM to 12:20 PM
Sponsor: Section on Risk Analysis
Abstract #301695 Presentation
Title: Identification of Gene-Gene and Gene-Environment Interactions in Genetic Association Studies
Author(s): Charles Kooperberg*
Companies: Fred Hutchinson Cancer Research Center

It is generally accepted that a substantial amount of the heritability of many complex traits is due to gene-gene and gene-environment interactions. Because of the large number of multiple comparisons when considering "all" possible interactions, the power to identify them is typically small,explaining the limited success of identifying such interactions. We will discuss various strategies to increase the power for such analyses.

Authors who are presenting talks have a * after their name.

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