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Activity Number: 7 - Fiber Bundles in Statistical Inference and Probability
Type: Invited
Date/Time: Sunday, July 28, 2019 : 2:00 PM to 3:50 PM
Sponsor: IMS
Abstract #300564
Title: A Statistical Pipeline for Feature Selection and Association Mapping with 3D Shapes
Author(s): Lorin Crawford*
Companies: Brown University
Keywords: Topological Data Analysis; Nonlinear regression; Gaussian processes; Variable selection; Shape statistics

It has been a longstanding challenge to implement an analogue of variable selection with 3D shapes as the covariates in a regression model. Here, we present SINATRA, a statistical pipeline for sub-image selection where the goal is to identify the physical features of 3D shapes that best explain the variation between two trait classes. A key insight is that, one can use tools from differential topology to transform objects represented as meshes into a collection of vectors (with little to no loss of information about their natural structure). Since this topological transformation is invertible, SINATRA uses interpretable machine learning to map significant vector indices back onto the original shapes — thus, highlighting the physical 3D shape characteristics that best distinguish members in the two groups. As an application of our pipeline, we conduct feature selection on a dataset consisting of mandibular molars from five different genera of New World Monkeys and examine which physical properties of their teeth best characterize their dietary regimens.

Authors who are presenting talks have a * after their name.

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