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Activity Number: 383 - Experimental Design Applications in the Pharmaceutical Industry
Type: Invited
Date/Time: Tuesday, July 30, 2019 : 2:00 PM to 3:50 PM
Sponsor: Section on Physical and Engineering Sciences
Abstract #300209 Presentation
Title: Experimental Design in the Pharmaceutical Industry
Author(s): Brad Evans*
Companies: Pfizer, Inc
Keywords: Design of Experiments; Central Composite; Definitive Screening; Effect Sparsity; Model Selection

Gaining process and product understanding is a key element in Pharmaceutical Drug Development. An efficient way to obtain this knowledge is through application of definitive screening designs and other classical statistical experimental designs (DoE). Here, even in application of DoE, “fit for purpose” designs should be selected considering project timelines, resources, effect sparsity, prior knowledge and project goals. The result of these considerations may produce quite different designs from one project to the next. This talk will provide examples of these tradeoffs using illustrative case studies.

Authors who are presenting talks have a * after their name.

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