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CC = Vancouver Convention Centre   F = Fairmont Waterfront Vancouver
* = applied session       ! = JSM meeting theme

Activity Details

129 ! Mon, 7/30/2018, 8:30 AM - 10:20 AM CC-West 210
Adaptive Design - 1 — Contributed Papers
Biopharmaceutical Section
Chair(s): John Han
8:35 AM Basket Trial Design Using Bayesian Model Averaging
Matthew Psioda, University of North Carolina; Jiawei Xu, University of North Carolina; Qi Jiang, Amgen; Chunlei Ke, Biogen; Zhao Yang, Amgen Inc; Joseph G Ibrahim, University of North Carolina Chapel Hill
8:50 AM Formulation of Data Monitoring Committee Recommendations for Adaptive Design Clinical Trials

Navneet Hakhu, Axio Research
9:05 AM Efficient Two-Stage Designs and Proper Inference for Animal Studies

Chunyan Cai, UT Health Science Center at Houston; Jin Piao, University of Southern California; Jing Ning, The University of Texas M.D. Anderson Cancer Center; Xuelin Huang, University of Texas MD Anderson Cancer Center
9:20 AM How to Inform and Revise Dose in Pediatric Program --- Some Statistical and Strategic Thinking

Yang Liu, Merck & Co Inc; Anne Chain, Merck; Rebecca Wrishko, Merck; Man (Mandy) Jin, Merck & Co., Inc.; Elizabeth Schaeffer, Merck; Kara Bickham, Merck
9:35 AM Specification Setting - an Adaptive Approach

Brad Evans, Pfizer, Inc
9:50 AM A Novel Framework for Bayesian Response-Adaptive Randomization
Jian Zhu, Takeda; Ina Jazic, Harvard University; Yi Liu, Takeda Pharmaceuticals
10:05 AM Closed-Form Solutions for Group Sequential Design in Survival Trials with Non-Proportional Hazards
Jianliang Zhang, Medimmune, LLC; Erik Pulkstenis, AbbVie