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Activity Number: 37 - Statistical Issues Specific the Therapeutic Areas - 1
Type: Contributed
Date/Time: Sunday, July 29, 2018 : 2:00 PM to 3:50 PM
Sponsor: Biopharmaceutical Section
Abstract #330522 Presentation
Title: Cure Survival Data in Oncology Studies
Author(s): Shih-Yuan Lee*
Companies: Takeda
Keywords: Cure; Oncology; Survival Distribution

For some cancers especially in the early diagnosis, the chance of having disease progression or death could be very small after a certain time point and a portion of patients could be considered as "cured". This phenomenal could be illustrated by the flat tail in an estimated K-M survival curve. In this setting, traditional distributions such as the exponential or the weibull distribution to generate survival data will not be appropriate. This paper will demonstrate alternative parametric and non-parametric approaches to generate cure survival data and illustrate how this could be applied in oncology studies.

Authors who are presenting talks have a * after their name.

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