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Activity Number: 68 - Personalized/Precision Medicine I
Type: Contributed
Date/Time: Sunday, July 29, 2018 : 4:00 PM to 5:50 PM
Sponsor: Biometrics Section
Abstract #329310
Title: Adjusting a Subject-Specific Timing of Event in Longitudinal Studies
Author(s): Hyunkeun Cho* and Seonjin Kim and Myunghee Lee
Companies: University of Iowa and Miami University and Weill Cornell Medical College
Keywords: Basis function approximation; Longitudinal trajectories; Piecewise regression; Quadratic inference function; Varying coefficient

In biomedical studies, longitudinal measurements are collected in an effort to understand a trend of response variables over time and a subject-specfic timing of event often has a significant influence on the trend. In this talk, we will introduce several interesting scientic questions that arise in the clinical study and prospective study, respectively, and provide the timing-of-event dependent model that address the scientific questions. This modeling is very appealing to researchers in that this allows us to explore not only the dynamic trend of outcomes over time, but also how the changes in the trend is influenced by the subject-specific timing of event. The proposed model is fitted to real data from the aforementioned studies, and the results of data analyses will be also discussed in the talk.

Authors who are presenting talks have a * after their name.

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