Abstract:
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We investigate optimal designs under the second-order least squares estimator for linear and nonlinear regression models. We derive the number of support points in A-, c- and D-optimal designs for various models analytically, and we also discuss numerical algorithms for finding optimal designs for any linear and nonlinear regression models. The algorithms are based on the semi-definite programming in convex optimization, and they are powerful to solve optimal design problems with hundreds of variables. Several applications will be presented.
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