| 
                            Activity Number:
                            
                         | 
                        
                            
                            273 
                            	- Statistical Analysis of Complex Imaging Data
                         | 
                    
                    
                        | 
                            Type:
                         | 
                        
                            Invited
                         | 
                    
                    
                        | 
                            Date/Time:
                         | 
                        
                            Tuesday, July 31, 2018 : 8:30 AM to 10:20 AM
                         | 
                    
                    
                        | 
                            Sponsor:
                         | 
                        
                            Section on Statistics in Imaging
                         | 
                    
                
                    
                        | 
                            Abstract #326472
                         | 
                        
                               
                                            
                                                Presentation 
                                            
                                            
                         | 
                    
                    
                        | 
                            Title:
                         | 
                        
                            Calculating a Generated Effect Modifier (GEM) for Treatment Selection Based on Imaging Data
                         | 
                    
                
                
                    | 
                        Author(s):
                     | 
                    
                        Todd Ogden* and Hyung Park and Eva Petkova and Thaddeus Tarpey 
                     | 
                
                
                    | 
                        Companies:
                     | 
                    
                        Columbia University and Columbia University and NYU School of Medicine and Wright State University 
                     | 
                
                
                    | 
                        Keywords:
                     | 
                    
                        
                            precision medicine; 
                            EEG; 
                            treatment regime 
                     | 
                
                
                    | 
                        Abstract:
                     | 
                    
                         
                            A major goal in precision medicine is to make optimal patient-specific treatment decisions using data observed at baseline.  For the treatment of neuropsychiatric disorders, available data may include clinical variables and measures of bevavioral/cognitive performance, as well as complex imaging data.  We will present methods for (1) determining low-dimensional projections of all these data that are useful for describing differential treatment response; and (2) for estimating nonparametrically defined link functions based on these projections for each potential treatment.  The resulting model can potentially provide powerful tools for precision medicine.    
                         
                     | 
                
                
                
                    Authors who are presenting talks have a * after their name.