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CC = Baltimore Convention Center,    H = Hilton Baltimore
* = applied session       ! = JSM meeting theme

Activity Details

620 * ! Thu, 8/3/2017, 8:30 AM - 10:20 AM CC-343
Dose-Finding for Monotherapy and Combination Therapy in Oncology and Other Complex Studies — Contributed Papers
Biopharmaceutical Section
Chair(s): Godwin Yung, Takeda Pharmaceutical
8:35 AM Dose Selection in Phase 2 Studies for a Drug Combination Using a Response Surface Modeling Technique Hongtao Zhang, AbbVie Inc. ; Jingjing Gao, AbbVie Inc. ; Qiming Liao, AbbVie Inc. ; Alan Hartford, AbbVie ; Jyotirmoy Dey, AbbVie Inc.
8:50 AM Incorporating Pharmacokinetic Assessment in Bayesian Phase I Trial Design in Oncology Area Kentaro Takeda, Astellas Pharma Global Development, Inc. ; Kanji Komatsu, Astellas Pharma Inc. ; Satoshi Morita, Kyoto University Graduate School of Medicine
9:05 AM Impact of Mis-Specified Prior in Combination Dose Finding Lixia Pei, Janssen Research & Development
9:20 AM Design of Phase I/II Drug Combination Cancer Trials Using CRM and Adaptive Randomization Mourad Tighiouart, Cedars-Sinai Medical Center ; Matthieu Clertant, Cedars-Sinai Medical Center
9:35 AM A Personalized Bayesian Information-Driven Dose-Finding Design Ilaria Domenicano, Dana-Farber Cancer Institute/University of Rome
9:50 AM Multiplicity Adjustment in Two Dose-Response Study Examples Li He, Merck Research Laboratories ; Joseph Heyse, Merck & Co., Inc.
10:05 AM Continual Reassessment Method for Partially Ordered Groups Bethany Horton, The University of Virginia ; Nolan Wages, The University of Virginia ; Mark Conaway, The University of Virginia
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