Legend:
CC = Baltimore Convention Center, H = Hilton Baltimore
* = applied session ! = JSM meeting theme
Activity Details
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458 * !
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Wed, 8/2/2017,
8:30 AM -
10:20 AM
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CC-319
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New Challenges in Subgroup Analyses and Enrichment Designs — Topic Contributed Papers
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Biopharmaceutical Section
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Organizer(s): Frank Bretz, Novartis AG
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Chair(s): Rosanne Lane, Janssen Research & Development, LLC
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8:35 AM
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Identification of Subgroups with Heterogeneous Treatment Effect in Dose-Response Studies
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Bjorn Bornkamp, Novartis Pharma AG ; Marius Thomas, Novartis
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8:55 AM
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Improving Subgroup Identification: Type I Error Control, Power, and the Quality of Subgroups
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Lei Shen, Eli Lilly and Company
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9:15 AM
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Sample Size Calculation in Confirmatory Subgroup Analyses
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Dong Xi, Novartis Pharmaceuticals Corporation ; Frank Bretz, Novartis AG ; Ekkehard Glimm, Novartis
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9:35 AM
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Stochastic Optimization of Adaptive Enrichment Designs for Two Subpopulations
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Michael Rosenblum, Johns Hopkins University ; Aaron Fisher, Harvard University-Department of Biostatistics ; Joshua A Betz, Johns Hopkins University ; Jon Steingrimsson, Johns Hopkins University
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9:55 AM
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Estimand in Evaluating Predictive or Selection Markers Using Enrichment Design in Clinical Trials
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Jingjing Ye, FDA
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10:15 AM
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Floor Discussion
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