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Activity Number: 299 - Survival and Recurrent Events in Epidemiology
Type: Contributed
Date/Time: Tuesday, August 1, 2017 : 8:30 AM to 10:20 AM
Sponsor: Section on Statistics in Epidemiology
Abstract #323980 View Presentation
Title: Investigating the Impact of Blood Pressure Lowering Medications on Blood Pressure Distributions
Author(s): Saryet Kucukemiroglu* and Dan McGee
Companies: Florida State University and Florida State University
Keywords: anti-hypertensive medications ; blood pressure distribution ; censoring ; maximum likelihood estimation
Abstract:

The use of blood pressure lowering medications has been increasing since its introduction in the mid-1950s. As a result, the use of anti-hypertensive treatments has affected the distribution of blood pressure in populations. In this study, we reconstruct systolic blood pressure distributions in populations if no treatment for hypertension were available. Censored lognormal samples were used to perform maximum likelihood estimation to find the parameters of the underlying distributions. The results showed that we can estimate the distribution of naturally occurring blood pressure in populations fairly accurately using censored data. Future research will explore the regression dilution bias associated with anti-hypertensive medications.


Authors who are presenting talks have a * after their name.

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