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Activity Number:
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651
- Perception and Use of Adaptive Designs in Industry and Academia: Comparison of the Four DIA Adaptive Design Scientific Working Group Surveys Conducted from 2000 Through 2015
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Type:
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Topic Contributed
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Date/Time:
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Thursday, August 3, 2017 : 10:30 AM to 12:20 PM
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Sponsor:
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Biopharmaceutical Section
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Abstract #323124
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View Presentation
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Title:
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Motivation and Design of the DIA Adaptive Design Scientific Working Group (DIA ADSWG) Survey for the Perception and Use of Adaptive Designs in Pharmaceutical Clinical Development
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Author(s):
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Alan Hartford*
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Companies:
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AbbVie
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Keywords:
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adaptive designs ;
sample size re-estimation ;
enrichment ;
interim analysis ;
Bayesian ;
early stopping
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Abstract:
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The motivation and design of the DIA Adaptive Design Scientific Working Group (DIA ADSWG) survey for the perception and use of adaptive designs (ADs) will be provided and contrasted with their previous surveys. The methods for implementation of the survey including how the sample was chosen and a summary of who responded will also be presented. The limitations of the survey, including where there could be possible bias, will be discussed.
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Authors who are presenting talks have a * after their name.
