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Activity Number:
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243
- Contributed Poster Presentations: Biopharmaceutical Section
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Type:
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Contributed
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Date/Time:
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Monday, July 31, 2017 : 2:00 PM to 3:50 PM
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Sponsor:
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Biopharmaceutical Section
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Abstract #323094
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Title:
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A Curtailed Design for Selecting the t Best Among Bernoulli Treatments and a Control
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Author(s):
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Mingyue Wang* and Pinyuen Chen
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Companies:
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Syracuse University and Syracuse University
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Keywords:
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Binomial Distribution ;
Least Favorable Configuration ;
Ranking and Selection
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Abstract:
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We propose a hybrid two-stage design for selecting the t best of k (k > t > 1) experimental Bernoulli treatments and a controlled Bernoulli treatment. The design uses a curtailment for possible early decision which achieves the same significance level and power as those of non-curtailed design. We adopt the selection-and-testing design considered by Thall, Simon, and Ellenberg (1988), but with a different goal: selecting among k treatments the t (t < k) best treatments and to compare them to the control. The selection stage of the design selects the t best provided that they are significantly better than other treatments and the control. The testing stage tests whether the selected two are superior to the control.
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Authors who are presenting talks have a * after their name.
