Activity Number:
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333
- SPEED: Biopharmaceutical Statistics, Medical Devices, and Mental Health
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Type:
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Contributed
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Date/Time:
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Tuesday, August 1, 2017 : 10:30 AM to 12:20 PM
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Sponsor:
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Section on Medical Devices and Diagnostics
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Abstract #322909
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Title:
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Propensity Score Methods for Analysis Time-To-Event Data
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Author(s):
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Haiying Lin*
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Companies:
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Keywords:
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Propensity score ;
observational study ;
Medical Device ;
time-to-event outcomes
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Abstract:
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Although randomized clinical trials are the gold standard for assessing the safety and efficacy of medical products, they may not always be feasible or ethical in practice. Researchers often have to rely on observational studies. Limitations of observational studies (e.g. lack of treatment assignment control) may lead to imbalanced characteristics between treatment groups, and consequently produce biased estimates of the treatment effects. A commonly used approach for reducing biases is propensity score (PS) methodology. In this presentation, a medical device case study with time-to-event outcome will be used to evaluate the performance of PS methods. Additional simulations will be carried out to compare various approaches.
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Authors who are presenting talks have a * after their name.
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