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Activity Number: 230 - Longitudinal Data Analysis
Type: Contributed
Date/Time: Monday, July 31, 2017 : 2:00 PM to 3:50 PM
Sponsor: Biometrics Section
Abstract #322495
Title: Clustered Binomial Data Analysis by Modified Generalized Estimating Equations
Author(s): Xuemao Zhang*
Companies: East Stroudsburg University
Keywords: Clustered binomial data ; Extra-binomial variation ; Generalized estimating equations ; Variance function
Abstract:

Extra-binomial variation in clustered binomial data is frequently observed in biomedical and observational studies. The usual generalized estimating equations (GEE) method treats the extra-binomial parameter as a constant across all clusters. In this paper, a two-parameter variance function modeling the extraneous variance is proposed to account for heterogeneity among clusters. The new approach allows modeling the extra-binomial variation as a function of the mean and binomial size.


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