Online Program Home
  My Program

Abstract Details

Activity Number: 309 - Statistical Topics in Precision Medicine
Type: Invited
Date/Time: Tuesday, August 1, 2017 : 10:30 AM to 12:20 PM
Sponsor: IMS
Abstract #321862
Title: New Adaptive Designs of Clinical Trial for Precision Medicine
Author(s): Feifang Hu*
Companies: George Washington University
Keywords: Adaptive Design ; Covariate Adaptive ; Biomarkers ; Randomization ; Power ; Sequential design
Abstract:

Precision medicine is the systematic use of information pertaining to an individual patient to select or optimize that patient's preventative and therapeutic care. With today's modern technology and big data, it is much easier to identify important biomarkers that may associate with certain diseases and their treatments. To design a clinical trial for precision medicine, one should include these important biomarkers. In this talk, we will propose a new family of covariate-adjusted response-adaptive designs, which incorporate these biomarkers as well as the responses. Advantages of the proposed methods are demonstrated through both theoretical and numerical studies. Some further statistical issues are also discussed.


Authors who are presenting talks have a * after their name.

Back to the full JSM 2017 program

 
 
Copyright © American Statistical Association