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Activity Number: 114
Type: Topic Contributed
Date/Time: Monday, August 1, 2016 : 8:30 AM to 10:20 AM
Sponsor: Committee on Career Development
Abstract #320696 View Presentation
Title: Conditional Logistic Regression in a Cluster-Specific M-to-M Treatment-Control Study with Binary Outcomes
Author(s): Zhulin He* and Gabriel Demuth and Zhengyuan Zhu
Companies: Iowa State University and Iowa State University and Iowa State University
Keywords: Conditional logistic regression ; Treatment-control design ; Binary outcomes ; Ordinary logistic regression ; Cluster-specific
Abstract:

Conditional logistic regression (CLR) method is derived by maximizing the conditional likelihood based on the sum of outcomes in each cluster. Using CLR, we can estimate the parameters of interest without estimating unwanted cluster-level nuisance parameters. Our main interest is to study the performance of CLR comparing with ordinary logistic regression (OLR) in a m:m treatment-control design with binary outcomes, where m is a study design factor. We compare CLR and OLR estimators under different designs indexed by the design factor m. We also illustrate the results with simulation studies and an application of National Resources Inventory image study.


Authors who are presenting talks have a * after their name.

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