Abstract Details
Activity Number:
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325
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Type:
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Contributed
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Date/Time:
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Tuesday, August 11, 2015 : 8:30 AM to 10:20 AM
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Sponsor:
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Biopharmaceutical Section
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Abstract #316860
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View Presentation
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Title:
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Identifying Treatment Responder Group Using Multiple Biomarkers
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Author(s):
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Zhaoling Meng* and Hui Quan and Tianle Chen
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Companies:
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Sanofi-Aventis and Sanofi and Biogen
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Keywords:
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treatment responder ;
biomarker selection ;
type I error control
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Abstract:
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Biomarkers hold tremendous promises in modern medicine such as tailoring a therapy to a better patient responder population. It is unlikely one biomarker alone could reflect all pathological processes that are involved in complicated disorders. We present a regression-based approach with multiple biomarkers to identify the better treatment responder group and control type I error rate. The proposed approach is compared to a naive method and a LASSO based method.
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Authors who are presenting talks have a * after their name.
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