JSM 2015 Preliminary Program

Online Program Home
My Program

Abstract Details

Activity Number: 701
Type: Contributed
Date/Time: Thursday, August 13, 2015 : 10:30 AM to 12:20 PM
Sponsor: Biopharmaceutical Section
Abstract #316169
Title: A New Bayesian Dose-Finding Design for Drug Combination Trials
Author(s): Jin Xu* and Rongji Mu
Companies: East China Normal University and East China Normal University
Keywords: adaptive design ; dose finding ; drug combination
Abstract:

This paper considers the problem of finding maximum tolerated dose with targeted dose-limiting toxicity rate in drug combination trials. We propose a new Bayesian adaptive design with a novel model featuring (i) adaptive modelling, (ii) self-learning, and (iii) subjectivity free. We demonstrate the superiority of the proposed method by comparison with some popular competing methods.


Authors who are presenting talks have a * after their name.

Back to the full JSM 2015 program





For program information, contact the JSM Registration Department or phone (888) 231-3473.

For Professional Development information, contact the Education Department.

The views expressed here are those of the individual authors and not necessarily those of the JSM sponsors, their officers, or their staff.

2015 JSM Online Program Home