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Activity Number: 659
Type: Contributed
Date/Time: Thursday, August 13, 2015 : 8:30 AM to 10:20 AM
Sponsor: Biopharmaceutical Section
Abstract #315123
Title: Using Tree-Based Methods for Identifying Predictive Biomarker in Clinical Trials
Author(s): Michael Man* and Wei-Yin Loh
Companies: and University of Wisconsin
Keywords: biomarker ; predictive ; tree-based ; tailoring
Abstract:

Identifying predictive biomarker for patient tailoring is becoming more and more important for drug development. Multi-marker approaches have become more popular to complement single-marker analyses. Recently developed tree-based methods are particularly suitable for finding predictive biomarker in randomized trials with large number of candidate markers. A few examples will be provided to illustrate the methodology. Challenges and future direction will also be discussed.

Authors who are presenting talks have a * after their name.

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