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Activity Number: 661
Type: Invited
Date/Time: Thursday, August 13, 2015 : 10:30 AM to 12:20 PM
Sponsor: Biometrics Section
Abstract #314510 View Presentation
Title: Strategies on Genome-Wide Interaction Analysis Using Case-Parents Data
Author(s): Zhaoxia Yu*
Companies: UC Irvine
Keywords: gene-gene interaction ; case-parents
Abstract:

Testing gene-gene interaction is critical to understanding how genes jointly affect disease risk. However, identifying interactions is challenging, as the large number of tests not only raises computational concerns but also leads to the problem of multiple testing. Here we present strategies to address these challenges in testing gene-gene interactions using case-parents data on a genome-wide scale. Our strategies are applied to a genome-wide study of multiple sclerosis.


Authors who are presenting talks have a * after their name.

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