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234 * Mon, 8/4/2014, 2:00 PM - 3:50 PM CC-258C
Subgroup Analysis and Biomarkers — Contributed Papers
Biopharmaceutical Section
Chair(s): Sharon Murray, GlaxoSmithKline   
2:05 PM Challenges and New Approaches in Identifying Treatment Specific Subgroups That Are Commercially Viable with Binary Outcomes Lin Li, BioStat Solutions ; Tobias Guennel, BioStat Solutions ; Scott Marshall, BioStat Solutions
2:20 PM Simultaneous Inference for Joint Overall and Subgroup Confirmatory Hypothesis Testing Hui Wang, Palo Alto VA/CSPCC ; Ying Lu, Palo Alto VA CSPCC/Stanford University ; Ilana Belitskaya-Lévy, Palo Alto VA CSPCC ; Gheorghe Doros, Boston University School of Public Health ; Robert A. Lew, VA Cooperative Studies Program Coordinating Center ; Mei Chiung Shih, Stanford University School of Medicine ; Lu Tian, Stanford University
2:35 PM Adjusting for Misclassification in the Design and Analysis of Stratified Biomarker Clinical Trials Susan Halabi, Duke University ; Chen-Yen Lin, Eli Lilly and Company ; Aiyi Liu, NICHD
2:50 PM The Plan of Enrichment Designs for Dealing with High Placebo Response Xiangmin Zhang, University of Iowa ; Yeh-Fong Chen, FDA
3:05 PM Identify a Target Population for Future Clinical Trial Aiyang Tao, Novartis ; Lihui Zhao, Northwestern University ; Lee Jen Wei , Harvard ; Achim Guettner, Novartis
3:20 PM Greediness Reduction Interaction Tree Algorithm for Subgroup Analysis in Clinical Trials Yi-Fan Chen, University of Illinois at Chicago ; Lisa Weissfeld, University of Pittsburgh
3:35 PM A Predictive Modeling Approach to Identify Clinical Important Treatment Difference in a Subgroup: Fraternal Twins Method Max Kuhn, Pfizer ; Birol Emir, Pfizer ; Ed Whalen, Pfizer



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