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Activity Details

127 * Mon, 8/4/2014, 8:30 AM - 10:20 AM CC-258C
Bayesian Designs in Clinical Trials — Contributed Papers
Biopharmaceutical Section , International Society for Bayesian Analysis (ISBA)
Chair(s): Eric Frimpong, FDA   
8:35 AM Bayesian Adaptive Dose-Finding Designs in Drug Combination Clinical Trials Yuehui Wu, GlaxoSmithKline ; Tian Chen, GlaxoSmithKline
8:50 AM A Bayesian Approach to Incorporate Prior Information in Interim Decisionmaking with Internal DMC Gang Jia, Merck ; Bruce Binkowitz, Merck ; Paul DeLucca, Merck
9:05 AM Designing a Time-to-Event Bayesian Clinical Trial That Incorporates Historical Data Barry Eggleston, RTI International ; Catellier Diane, RTI International ; Joseph Ibrahim, University of North Carolina
9:20 AM A Bayesian Optimal Design Using Natural Conjugate Prior Families in Two-Arm, Randomized Phase II Clinical Trials with Endpoints from Exponential Families Wei Jiang, University of Kansas Medical Center ; Jo A. Wick, University of Kansas Medical Center ; Matthew S. Mayo, Kansas University Medical Center
9:35 AM Considerations on Bayesian Dose Window Escalation: Part II Xue Lin, FDA
9:50 AM A Simple Method for Predicting a Binomial Response Rate in a Bayesian Interim Analysis of a Single-Arm Trial When Observing Responses and Failures Requires Prolonged Follow-Up Gary Hantsbarger, Astellas
10:05 AM A Bayesian Confirmatory Factor Model for Familial Data with Multiple Outcomes Qiaolin Chen, Novartis ; Robert E. Weiss, University of California, Los Angeles ; Catherine A. Sugar, University of California, Los Angeles

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