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Activity Details


CE_24C Tue, 8/5/2014, 8:30 AM - 5:00 PM CC-160B
Causal Mediation Analysis — Professional Development Continuing Education Course
ASA , Section on Statistics in Epidemiology
The course will cover some of the recent developments in causal mediation analysis and provide practical tools to implement these techniques. Mediation analysis concerns assessing the mechanisms and pathways by which causal effects operate. The course will cover the relationship between traditional methods for mediation in epidemiology and the social sciences and new methods in causal inference. For dichotomous, continuous, and time-to-event outcomes, discussion will be given as to when the standard approaches to mediation analysis are valid. Using ideas from causal inference and natural direct and indirect effects, alternative mediation analysis techniques will be described when the standard approaches will not work. The no-confounding assumptions needed for these techniques will be described. SAS, SPSS and Stata macros to implement these techniques will be covered and distributed to course participants. The use and implementation of sensitivity analysis techniques to assess the how sensitive conclusions are to violations of assumptions will be covered. Discussion will be given to how such mediation analysis approaches can be extended to settings in which data come from a case-control study design. The methods will be illustrated by various applications. Familiarity with linear and logistic regression will be required to fully benefit from the course.
Instructor(s): Tyler VanderWeele, Harvard



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