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Activity Number: 501
Type: Contributed
Date/Time: Wednesday, August 6, 2014 : 10:30 AM to 12:20 PM
Sponsor: Biopharmaceutical Section
Abstract #313725
Title: Revisiting Risks Ratio and Properties of Corresponding Confidence Intervals
Author(s): Ramin Arani*+ and Ian Hirsch
Companies: AstraZeneca and AstraZeneca
Keywords: Risk Ratio ; Coverage Probability ; Moving Average ; Benefit-Risk Analysis
Abstract:

The ratio of two random variables such as risks ratio are commonly utilized in decision making in clinical trials and medical research. In this presentation we investigate properties of confidence intervals for risk ratio evaluated based on a proposed method compared to several well established methods. The metrics utilized in process is coverage probability and the moving average of the interval length. The results are utilized in the Benefit-Risk Ratio context.


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