Abstract Details
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Activity Number:
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459
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Type:
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Contributed
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Date/Time:
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Wednesday, August 6, 2014 : 8:30 AM to 10:20 AM
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Sponsor:
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Biopharmaceutical Section
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Abstract #313511
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Title:
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A Group Sequential Method for Testing Multiple Hypotheses
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Author(s):
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Aiying Chen*+ and Sanat K. Sarkar and Li He
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Companies:
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and Temple University and Merck
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Keywords:
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group sequential methods ;
familywise error rate ;
multiple hypotheses
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Abstract:
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In this paper, we consider developing a group sequential procedure for testing multiple hypotheses with a control over the familywise error rate in the strong sense. Our procedure incorporates the dependence structure among the test statistics corresponding to the multiple endpoints under normal distributional setting. Simulation studies show that it is more powerful and provides more reduction of the expected sample sizes compared to its relevant competitors.
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Authors who are presenting talks have a * after their name.
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