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Activity Number: 632
Type: Topic Contributed
Date/Time: Thursday, August 7, 2014 : 10:30 AM to 12:20 PM
Sponsor: Biopharmaceutical Section
Abstract #313300 View Presentation
Title: Implementation of NGS Genomics Data in Oncology Clinical Trials: Analytical Issues and Lessons Learned
Author(s): Ray Liu*+ and Feng Gao and Jacob Zhang
Companies: Takeda and Takeda and Takeda
Keywords: NGS ; biomarker ; clinical trial
Abstract:

Cancer is a highly complex and heterogeneous disease that is hard to treat. Next generation sequencing (NGS)-based technology has the potential to provide comprehensive genomics information on short turnaround time that can lead to better patient selection and ultimately personalized treatment decision. However, many unique practical and analytical issues need to be considered carefully when adapting NGS-based genomics data into oncology clinical trials. In this presentation we will share the experience and lessons learned, which can be used to better design future NGS-based clinical trials.


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