Development of a Scoring Algorithm and Classification Procedure for a Computerized Cognitive Assessment Tool

• Activity Number: 249
• Type: Contributed
• Date/Time: Monday, August 4, 2014 : 2:00 PM to 3:50 PM
• Sponsor: Section on Statistical Consulting
• Author(s): Laurel Chiappetta*+ and Gretchen Brauch and Lisa Morrow and Graham Ratcliffe and Anthony Zuccolotto and Amy Eschman and Judith Saxton
• Companies: Data Development Integration Verification Analysis and Psychology Software Tools and University of Pittsburgh Medical Center and Clinical Neuropsychology Services and Psychology Software Tools and Psychology Software Tools and Clinical Neuropsychology Services
• Keywords: cognitive impairment ; algorithm ; computerized assessment ; memory ; classification

Abstract

The Computer Assessment of Memory and Cognitive Impairment (CAMCI®) is a portable computerized tool designed to provide a valid assessment of cognitive function in older individuals in an outpatient setting. Normative data was collected on 536 individuals aged > 60 recruited in primary care and community sites. An algorithm involving CAMCI task scores was developed to produce a CAMCI total score that most accurately reflects an individual's level of cognitive function, and permits effective discrimination between groups identified on the basis of the clinical adjudication. Statistical methodology focused on the reduction of false positives and used a 3-group classification procedure allowing for the identification of a group with borderline cognitive dysfunction. A complete description of the re-sampling strategy, variable selection, test and training sample selection, algorithm development, classification procedure, and calibration/scaling of the final score are provided. When interpreted by a qualified healthcare professional, CAMCI will assist in the identification of patients with suspected cognitive impairment for whom further evaluation may be appropriate.