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Activity Number: 159
Type: Topic Contributed
Date/Time: Monday, August 4, 2014 : 10:30 AM to 12:20 PM
Sponsor: Biometrics Section
Abstract #312656
Title: A Robust Method for Correlated RNA Sequence Data
Author(s): Jinfeng Xu*+ and Hong Zhang
Companies: and Fudan University
Keywords: Count data ; RNA ; Poisson
Abstract:

We propose a model for analyzing correlated RNA sequence data by specifying a general mean-variance formula. It naturally extends the existing models and provides a more flexible tool. Fast algorithms are developed for its numerical implementation. Extensive simulation studies show that the approach exhibits superior robustness properties and perform favorably under a variety of settings. However, the competing approaches perform well only when their restrictive assumptions are met. In the real data applications, the new method also yields more interesting results.


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