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Activity Number: 318
Type: Topic Contributed
Date/Time: Tuesday, August 5, 2014 : 10:30 AM to 12:20 PM
Sponsor: ENAR
Abstract #312629
Title: A Semiparametric Threshold Regression Analysis with Flexible Covariate Effects
Author(s): Xin He*+ and Ran Ji and Mei-Ling Ting Lee
Companies: University of Maryland and University of Maryland and University of Maryland
Keywords: B-spline ; Spline approximation ; Survival analysis ; Threshold regression ; Wiener process
Abstract:

In this talk, we consider a semiparametric threshold regression model with flexible covariate effects. Specifically, we propose a B-spline approximation method to estimate nonlinear covariate effects on both the initial state and the rate of the process. Some graphical and numerical procedures are presented for model checking. Simulation studies are conducted for practical situations, and the methodology is applied to a study of knee osteoarthritis that motivated this investigation.


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