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Activity Number: 454
Type: Contributed
Date/Time: Wednesday, August 6, 2014 : 8:30 AM to 10:20 AM
Sponsor: Biometrics Section
Abstract #312244 View Presentation
Title: An Alternative Estimation Method for the Semiparametric Accelerated Failure Time Mixture Model
Author(s): Yinding Wang*+ and Jiajia Zhang
Companies: and University of South Carolina
Keywords: Survival analysis ; accelerated failure time mixture model ; EM algorithm ; Profile likelihood ; clinical trials
Abstract:

We proposed an alternative estimation method for the semiparametric accelerated failure time mixture model by incorporating the profile likelihood into the M-step of the EM algorithm. Our simulation study shows that the proposed method works as well as the existing method.


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