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Activity Number: 559
Type: Contributed
Date/Time: Wednesday, August 6, 2014 : 2:00 PM to 3:50 PM
Sponsor: ENAR
Abstract #311006
Title: Regression Analysis of Longitudinal Data with Informative Observation Times
Author(s): Yang Li*+ and HaiYing Wang and Tony Sun and Xin He
Companies: University of North Carolina at Charlotte and University of New Hampshire and University of Missouri and University of Maryland
Keywords: informative observation times ; joint analysis approach ; longitudinal data analysis ; shared frailty models
Abstract:

Longitudinal data usually occur in medical follow-up studies in which a certain response process is observed at discrete times. Most existing approaches on longitudinal data analysis assumed that the observation times are independent of the response process either completely or given some covariates. We present a joint analysis approach in which the possible correlation is characterized by time-varying shared frailty models. Estimating equations are developed for the parameter estimation and a simulation study is conducted to assess the finite sample performance of the approach. The asymptotic properties of the proposed estimates are also given and the method is applied to an illustrative example.


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