Statistical Methodology Collaborations with Pharmaceuticals: Solving Important and Cutting Edge Applied Problems in Biomedical Research

• Activity Number: 621
• Type: Invited
• Date/Time: Thursday, August 7, 2014 : 10:30 AM to 12:20 PM
• Sponsor: SPAIG Committee
• Author(s): Joseph Ibrahim*+
• Companies: University of North Carolina
• Keywords: Clinical Trial ; Survival Analysis ; Longitudiunal Data ; Meta-analysis ; Missing Data

Abstract

Statistical methodological research has become very interdisciplinary in nature, and modern innovative advances and high impact statistical research typically now requires a team of methodologists, practitioners, and subject-matter experts. A recent success model for such collaborations involves academia working together with pharmaceuticals to work on important, applied, high impact design and analysis problems in clinical trials and observational studies, survival analysis, longitudinal data, and meta-analysis. Such collaborations have introduced academic statistical researchers to new statistical problems that would not have been encountered in a typical academic environment. In this talk, we highlight some examples of recent success stories of collaborations from the UNC Center for Innovative Clinical Trials (CICT). The CICT was established in 2007 to foster close collaborations between academia and pharmaceuticals for solving important and long-standing methodological problems in the design and analysis of clinical trials, as well as for developing new modeling techniques, computational methods, and software tools that emerge from such collaborations.