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Activity Details


CE_26C Tue, 8/6/2013, 1:00 PM - 5:00 PM W-Ville-Marie
Statistical Methods in Genetic Association Studies — Continuing Education Course
ASA , Biometrics Section
Instructor(s): Danyu Lin, Univ of North Carolina
Association studies have become the primary tool for the genetic dissection of complex human diseases, and genetic association has played an increasingly important role in biomedical research. This course provides an overview of the statistical methods that have recently been developed for the designs and analysis of genetic association studies. Specific topics include genome-wide association studies, case-control sampling and retrospective likelihood, secondary phenotypes in case-control studies, haplotypes and untyped SNPs, population stratification, meta-analysis, multiple testing, next-generation sequencing studies, rare variants, trait-dependent sampling, variable selection, and risk prediction.



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