Legend: Palais des congrès de Montréal = CC, Le Westin Montréal = W, Intercontinental Montréal = I
A * preceding a session name means that the session is an applied session.
A ! preceding a session name means that the session reflects the JSM meeting theme.
A * preceding a session name means that the session is an applied session.
A ! preceding a session name means that the session reflects the JSM meeting theme.
Activity Details
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| CE_09C | Sun, 8/4/2013, 8:30 AM - 5:00 PM | W-St. Antoine | |
| Recent Advances in Bayesian Adaptive Clinical Trial Design — Continuing Education Course | |||
| ASA , Section on Bayesian Statistical Science | |||
| Instructor(s): Peter Thall, M.D. Anderson Cancer Center, Brian Hobbs, The University of Texas M.D. Anderson Cancer Center | |||
| This one-day short course will cover a variety of recently developed Bayesian methods for the design and conduct of adaptive clinical trials. Emphasis will be on practical application, with the course structured around a series of specific illustrative examples. Topics to be covered will include: (1) using historical data in both planning and adaptive decision making during the trial; (2) using elicited utilities or scores of different types of multivariate patient outcomes to characterize complex treatment effects; (3) characterizing and calibrating prior effective sample size; (4) monitoring safety and futility; (5) eliciting and establishing priors; and (6) using computer simulation as a design tool. These methods will be illustrated by actual clinical trials, including cancer trials involving chemotherapy for leukemia and colorectal cancer, stem cell transplantation, and radiation therapy, as well as trials in neurology and neonatology. The illustrations will include both early phase trials to optimize dose, or dose and schedule, and randomized comparative phase III trials. | |||
2013 JSM Online Program Home
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