Abstract Details
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Activity Number:
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454
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Type:
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Other
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Date/Time:
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Wednesday, August 7, 2013 : 8:30 AM to 10:20 AM
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Sponsor:
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ASA
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| Abstract - #310394 |
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Title:
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RNAseq: Some Statistical Challenges
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Author(s):
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Rafa Irizarry*+
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Companies:
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JHSPH
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Keywords:
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Abstract:
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RNA-sequencing technology is on pace to replace microarrays as the most common approach to measure gene expression. This transition is being driven by the rapid decline in cost of sequencing and the flexibility of sequencing technology to measure genomic events such as transcription of novel regions, allele specific transcription, and alternative transcription. In this talk, I will give a brief introduction to gene expression and related measurement technologies, describe some of the statistical issues with a focus on assessing and dealing with unwanted variability, and give a short summary of our ongoing work related to detecting differentially expressed regions of the genome. I will show some examples from a clinical datasets.
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Authors who are presenting talks have a * after their name.
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