Abstract Details
Activity Number:
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137
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Type:
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Contributed
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Date/Time:
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Monday, August 5, 2013 : 8:30 AM to 10:20 AM
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Sponsor:
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Section on Statistics in Epidemiology
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Abstract - #310233 |
Title:
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Application of a Reconstructed Population Method to the Global Enteric Multicenter Study Mortality Data
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Author(s):
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Yukun Wu*+ and Diluba Nasrin and Tamer Farag and Karen Kotloff and Myron Levine and Halvor Sommerfelt and William C. Blackwelder
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Companies:
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University of Maryland School of Medicine and University of Maryland School of Medicine and University of Maryland School of Medicine and University of Maryland School of Medicine and University of Maryland School of Medicine and University of Bergen and University of Maryland School of Medicine
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Keywords:
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case-control study with follow-up ;
reconstructed population
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Abstract:
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Sommerfelt et al. (Clinical Infectious Diseases, 2012) introduced a reconstructed population method (RPM), which can estimate the association between risk factors and outcomes other than the one that defines case-control status. We apply this method to data from the Global Enteric Multicenter Study (GEMS), the centerpiece of which was a case-control study designed to describe acute moderate-to-severe diarrhea (MSD) in children 0-59 months of age. A feature of GEMS was follow-up at approximately 60 days after enrolling study participants, when the occurrence of outcomes other than MSD was determined. Using a Cox regression model, we use the RPM to estimate the hazard ratio of death given the presence of several pathogens, and we consider methods for estimating the variability of model coefficients.
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Authors who are presenting talks have a * after their name.
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