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Activity Number: 494
Type: Contributed
Date/Time: Wednesday, August 7, 2013 : 8:30 AM to 10:20 AM
Sponsor: IMS
Abstract - #310188
Title: A Branching Process Model of Prion Dynamics
Author(s): Peter Olofsson*+ and Suzanne Sindi
Companies: Trinity University and University of California, Merced
Keywords:
Abstract:

Prions are infectious agents composed of misfolded proteins, responsible for illnesses such as mad cow disease in cattle and Creutzfeldt--Jakob disease in humans. We create a branching process model for yeast cells to describe how prions grow inside the cell and how they are transmitted from mother to daughter cell. We compare our model predictions to laboratory data and use it to estimate unknown parameters.


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