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Activity Number: 294
Type: Topic Contributed
Date/Time: Tuesday, August 6, 2013 : 8:30 AM to 10:20 AM
Sponsor: Mental Health Statistics Section
Abstract - #309859
Title: Pain Intensity, Pain Interference, and Depression in Patients Treated for Low Back Pain: Linear Growth Model Analysis
Author(s): Dennis Revicki*+ and Wen-Hung Chen and Dagmar Amtmann and Karon Cook
Companies: United BioSource Corporation and United BioSource Corporation and University of Washington and Northwestern University
Keywords: Pain intensity ; Depression ; Pain interference ; Linear growth models ; Low back pain ; Longitudinal analyses

Introduction: Pain intensity and pain interference are related in chronic pain samples. Patients with low back pain frequently report depression. Few studies have examined impact of depression on the relationship between pain intensity and pain interference. Methods: 218 patients treated with epidural steroid injection for low back pain were recruited at and followed for 3 months. Measures included the Brief Pain Inventory and PROMIS pain interference, depression, and physical function scales. Linear growth model analyses with time dependent covariates were used to evaluate the longitudinal relationship among pain and other measures, adjusting for age, gender, and baseline physical function. Results: Mean (SD) age was 54.3 (14.7) and were 56% female and 84% Caucasian. Models showed good fit (CFI=0.99, RMSEA=0.013). Patients with greater rates of change in pain intensity reported increased in pain interference ( = 0.52-0.75, p < 0.001). Increased depression severity exacerbated increases in pain interference ( = 0.11-0.30, p < 0.05). Conclusions: Relationships between changes in pain intensity and interference were impacted and moderated by changes in depression severity.

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