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Activity Number: 239
Type: Contributed
Date/Time: Monday, August 5, 2013 : 2:00 PM to 3:50 PM
Sponsor: Biometrics Section
Abstract - #309823
Title: An Alternative REML Estimation of Covariance Matrices in Linear Mixed Models
Author(s): Erning Li*+ and Mohsen Pourahmadi
Companies: University of Iowa and Texas A&M University
Keywords: Cholesky decomposition ; Covariance matrices ; Longitudinal data ; Mixed models ; Restricted or residual maximum likelihood
Abstract:

We propose a data-driven procedure for modeling covariance matrices in linear mixed-effects models with minimal distributional assumption on the random effects. It is based on elimination of the random effects using a transformation of the response variable. The approach makes it possible for the first time to disentangle the covariance matrices and model them separately. The performance of the proposed method is assessed via simulations and real data.


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