Abstract Details
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Activity Number:
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194
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Type:
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Contributed
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Date/Time:
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Monday, August 5, 2013 : 10:30 AM to 12:20 PM
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Sponsor:
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Biometrics Section
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| Abstract - #309793 |
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Title:
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NextAllele: A Bioinformatic Pipeline to Infer Full-Length Haplotypes
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Author(s):
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Edward Roualdes*+
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Companies:
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Deptartment of Statistics
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Keywords:
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next generation sequence ;
phylogenetic ;
bioinformatic
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Abstract:
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NextAllele is a set of bioinformatic tools that phases haplotypes across multiple loci for any number of individual's next generation sequence data. After a number of processing steps, with help from BLAST, a likelihood ratio test, a version of Hohenlohe's 2010 LRT, is used to infer SNPs at a single nucleotide site. Thus, based on this likelihood ratio test we infer the two most likely haplotypes at each loci for each individual. NextAllele's output can be used to aid phylogenetic and population-genetic analyses.
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Authors who are presenting talks have a * after their name.
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