Abstract Details
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Activity Number:
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515
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Type:
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Topic Contributed
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Date/Time:
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Wednesday, August 7, 2013 : 10:30 AM to 12:20 PM
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Sponsor:
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Health Policy Statistics Section
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| Abstract - #309678 |
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Title:
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Combining Single and Two-Group Outcome Risks/Comparisons from Multiple Studies of Safety
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Author(s):
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Nicholas Jewell*+
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Companies:
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University of California Berkeley
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Keywords:
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Pooling ;
Meta-analysis ;
Safety
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Abstract:
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Although an essential component of efficacy clinical trials, the assessment of adverse events is often not a primary outcome. As such, most unique trials have insufficient data to yield precise treatment comparisons regarding the frequency of adverse events. To achieve the latter, many 'similar' studies are often pooled to achieve greater precision. Here we consider some examples of pooling studies in both the single and multiple treatment scenarios with a view to illustrating common pitfalls in terms of both bias and variability.
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Authors who are presenting talks have a * after their name.
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