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Activity Number: 18
Type: Topic Contributed
Date/Time: Sunday, August 4, 2013 : 2:00 PM to 3:50 PM
Sponsor: Section on Statistical Computing
Abstract - #308519
Title: Integrative Analysis of Disparate Contaminated Data Sets
Author(s): Junrui Di*+ and Valeriy Korostyshevskiy
Companies: Georgetown University and Georgetown University
Keywords: integrative analysis ; disparate contaminated data ; JIVE ; robust JIVE
Abstract:

An important challenge posed by the omics revolution is the development of methods for integrated analyses of disparate biological data. Recently Lock et al. (2011) introduced a method called Joint and Individual Variation Explained (JIVE). We propose a robust version of JIVE using low-rank approximations based on robust singular value decomposition methods. Using a simulation study we investigate the performance of the robust JIVE method under different scenarios involving contaminated data.

Department of Biostatistics, Bioinformatics, and Biomathematics, Georgetown University 4000 Reservoir Road, NW, Washington DC, 20057-1484


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