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Activity Number: 80
Type: Contributed
Date/Time: Sunday, August 4, 2013 : 4:00 PM to 5:50 PM
Sponsor: Biopharmaceutical Section
Abstract - #308214
Title: Variable Selection by Combinatorial Optimization, with Application to Pharmacogenomics
Author(s): Joseph Levy*+ and Amir Tchelet
Companies: Teva Pharmaceuticals Industries and Teva Pharmaceutical Industries
Keywords: Variable Selection ; Prediction ; Pharmacogenomics ; Combinatorial Optimization
Abstract:

Given a set of observed variables that are associated with a response variable, it is often desired to select a subset of the observed variables that will enable predicting the value of Y.

We propose to approach the variable selection problem as a combinatorial optimization problem. Application of heuristics commonly used for such problems provide superior results. The approach will be demonstrated using data from one of Teva's recent pharmacogenomics studies.


Authors who are presenting talks have a * after their name.

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