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Activity Number: 294
Type: Topic Contributed
Date/Time: Tuesday, August 6, 2013 : 8:30 AM to 10:20 AM
Sponsor: Mental Health Statistics Section
Abstract - #308137
Title: Patient-Reported Outcomes and Endpoint Selection in Mental and Behavioral Health Research
Author(s): Laura Lee Johnson*+
Companies: National Center for Complementary and Alternative Medicine (NCCAM)
Keywords: patient reported outcomes ; PRO ; endpoint selection ; sleep ; depression ; item response theory

Measures and composite concepts useful in clinical practice and diagnosis may not translate into research and clinical trial endpoints. We will discuss endpoint introspection when using, or choosing not to use, PRO endpoints especially when comorbidities are common. Patient or person reported outcomes often focus on broad domains that measure several subdomains, for example a physical health domain may measure physical function, symptoms such as pain and fatigue, sleep/wake disturbance and other subdomains. Examples will come from depressed mood and sleep PROs.

Authors who are presenting talks have a * after their name.

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