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Activity Number: 521
Type: Topic Contributed
Date/Time: Wednesday, August 7, 2013 : 10:30 AM to 12:20 PM
Sponsor: Biometrics Section
Abstract - #307594
Title: Bayesian Methods to Identify Sequences with Species
Author(s): G. Brian Golding*+
Companies: McMaster University
Keywords: phylogenetics ; barcoding ; coalescent ; species identification ; segregating sites
Abstract:

DNA traces from humans can be quickly and accurately traced back to their source. With greater error, standardized DNA sequences from unknown species can be traced back to the species of their source. This problem involves evaluating the statistical evidence towards associating a sequence from a new individual with one group or another. I will outline a Bayesian method to quantify this uncertainty. The method developed is decision-theory based and makes use of a coalescent model. Since the evaluation of a coalescent is often a lengthy process requiring sensitive MCMCs, I also outline a method to approximate the coalescent using segregating sites and essentially integrate out the within species phylogeny.


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