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Activity Number: 457
Type: Invited
Date/Time: Wednesday, August 7, 2013 : 8:30 AM to 10:20 AM
Sponsor: Biometrics Section
Abstract - #307289
Title: Causal Mediation Analysis in Comparative Effectiveness Research
Author(s): Xiao-Hua Andrew Zhou*+ and Cheng Zheng
Companies: University of Washington and University of Washington
Keywords: Comparative effectiveness; propensity score; high-dimensional data
Abstract:

Mediation analysis is an important topic in comparative effectiveness research as it helps to understand why an intervention works. In this talk, we proposed a new mediation model for count data that does not require "sequential ignorability" assumption. We compared the proposed estimator with both Poisson and Negative binomial regression method assuming sequential ignorability in both simulation study and a real data problem. The results show that the proposed method performs well.


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