Abstract Details
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Activity Number:
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459
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Type:
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Invited
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Date/Time:
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Wednesday, August 7, 2013 : 8:30 AM to 10:20 AM
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Sponsor:
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SSC
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| Abstract - #307110 |
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Title:
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Measuring the Mortality Reductions Produced by Cancer Screening
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Author(s):
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James A. Hanley*+ and Zhihui(Amy) Liu and Erin Strumpf and Nandini Dendukuri
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Companies:
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McGill University and McGill University and McGill University and McGill University
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Keywords:
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cancer ;
screening ;
mortality
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Abstract:
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Current guidelines on cancer screening are based on data-analyses that ignore key principles of cancer screening. Consequently they underestimate the mortality reductions that would result from a sustained program. We formulate a statistical model that characterizes the delayed impact of each round of screening. A reanalysis of the year-specific data from five commonly cited screening trials suggests that a program of regular mammography screening, from age 50 to 69, would result in yearly breast cancer mortality reductions of at least 40%, rather than the approximately 20% reported by the 2009 US and 2011 Canadian Task Force meta-analyses, and the 2012 UK independent panel.
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Authors who are presenting talks have a * after their name.
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